Dr. Mario 64
Dr. Mario 64 — frequently asked questions
- What platforms is Dr. Mario 64 on?
- Dr. Mario 64 was released on Nintendo GameCube, Nintendo 64, iQue Player.
- When did Dr. Mario 64 release?
- Dr. Mario 64 was first released on April 8, 2001.
About Dr. Mario 64
The flu season has come about, and it's Dr. Mario's duty to use his Megavitamins to heal the people of the land. However, Wario, wanting to have the fame that Dr. Mario has, attempts to steal the Megavitamins, but to no avail. Afterwards, Mad Scienstein and Rudy the Clown (from Wario Land 3) steal the Megavitamins, and both Dr. Mario and Wario give chase.
Summary via IGDB.
Dr. Mario 64 on Wikipedia
Dr. Mario 64 is a 2001 tile-matching action puzzle game developed and published by Nintendo for the Nintendo 64. The game is an enhanced remake of Dr. Mario, which was originally released for the NES and Game Boy consoles in 1990, and is based around characters from the 2000 Game Boy Color game Wario Land 3. The game's soundtrack was composed by Seiichi Tokunaga, featuring arrangements of classic Dr. Mario tunes and new compositions. The game was released in North America on April 9, 2001.
Source: Wikipedia (text under CC BY-SA 4.0).
Game details
- Platforms
- Nintendo GameCube, Nintendo 64, iQue Player
- Developer
- Nintendo IRD
- Publisher
- Nintendo
- Game modes
- Single player, Multiplayer, Split screen
- Themes
- Comedy
- Series
- Mario
Details via IGDB.
Reception
Every version compared
Prices, contemporary reception and the studio credited for each release
| Platform | Year | Loose | Complete | Sealed | Period reviews | Fake risk |
|---|---|---|---|---|---|---|
| Nintendo 64 | 2001 | $29 | $63 | $307 | 10 reviews | Low |
Release timeline
- Nintendo 64Apr 8, 2001
- Nintendo GameCubeFeb 7, 2003
First release on each platform, from IGDB’s records of this game’s ports and editions. Remakes are separate games with their own pages, so they are not listed here.
We haven’t priced or authenticated the versions without a section on this page yet.
Collector value & authenticity
Nintendo 64 · PriceCharting sold data · Verified 2026-10-22
How often it sells
- Loose: about once a day
- Complete: about once a week
- Sealed: about 6 times a year
Sales frequency from PriceCharting's completed-sale records, as of 2026-10-22.
Price over time
- Loose
- Complete
A loose copy sold for about $25 in Jan 2007, $25 five years ago, and $28 as of Oct 2026.
Show as table
| Month | Loose | Complete |
|---|---|---|
| Jan 2007 | $25 | — |
| Jan 2008 | $25 | — |
| Jan 2009 | $16.84 | — |
| Jan 2010 | $14.45 | — |
| Jan 2011 | $9.50 | — |
| Jan 2012 | $8.24 | — |
| Jan 2013 | $12.45 | — |
| Jan 2014 | $10.50 | $40 |
| Jan 2015 | $13.50 | $31 |
| Jan 2016 | $15.50 | $31 |
| Jan 2017 | $16.95 | $29 |
| Jan 2018 | $17.24 | $37 |
| Jan 2019 | $18.74 | $40 |
| Jan 2020 | $18.79 | $40 |
| Jan 2021 | $28 | $57 |
| Jan 2022 | $30 | $87 |
| Jan 2023 | $35 | $72 |
| Jan 2024 | $24 | $76 |
| Jan 2025 | $30 | $71 |
| Jan 2026 | $30 | $71 |
| Oct 2026 | $28 | $63 |
Monthly price estimates from PriceCharting's completed-sale records, sampled quarterly, through Oct 2026.
Release record
| Territory | Date | Cartridge serial | Known board |
|---|---|---|---|
| North America | 9 April 2001 | NUS-NN6E-USA | NUS-01A-03 |
- Region
- NA
- Released
- 2001
- Authenticity
- Low
A competent four-player puzzle remake that came out late in the N64's life and still costs more than most of its library.
Dr. Mario 64 is Nintendo's enhanced remake of its 1990 NES and Game Boy puzzle game, released in North America on April 9, 2001. It uses characters from Wario Land 3, and Seiichi Tokunaga composed the soundtrack, mixing arrangements of classic Dr. Mario tunes with new pieces. It has story-mode cinemas between stages.
Electronic Gaming Monthly's June 2001 preview described it as a graphical facelift of the classic, arriving to prop up a thin spring for the N64. It was a runner-up for GameSpot's Best Nintendo 64 Game award for the year, which went to Paper Mario.
How it was made
Developed and published by Nintendo. Seiichi Tokunaga composed the soundtrack.
What the press said at the time
| GameRankings (aggregate) | 70.03% | |
| Metacritic (aggregate) | 71 / 100 | |
| Electronic Gaming Monthly | 6.8/10 | |
| Game Informer | 8.5/10 | |
| GamePro | 3.875/5 | |
| GameRevolution | C | |
| GameSpot | 7/10 | |
| IGN | 5/10 | |
| N64 Magazine | 43% | |
| Nintendo Power | 4/5 |
“played Pokémon Puzzle League to their wits' end will find Dr. Mario to be great CPR for their waning system.”
“Even Dr. Mario 64, which is 90 percent rehashed material, virtually devoid of unlockables, and darn ugly in multiplayer, can awaken a gamer in denial. It’s $30 well-spent, whether you’ve played prior versions or not.”
Undated scores are from the review table in the game's Wikipedia article, limited to reviews of the Nintendo 64 version.
How the Nintendo 64 version differs
Reviewers noted up to four players can play at once in any of three competitive games, with a two-player versus mode as well.
The cartridge was first released in North America in 2001; PAL territories got the game only through Nintendo Classics in October 2021.
Also on other platforms
iQue Player
Before you buy
A North American release only. Loose it sits above the library median, though below the typical price of N64 games released in 2001, and the fake risk is low. A complete copy costs about double the loose price.
Dr. Mario 64 screenshots
Watch on YouTube
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